1. 多肽纳米化学及仿生合成

2. 面向健康医疗领域的鞣智电子材料与器件

（†共同第一作者，*通讯作者）

2024

11. Zhen-Yi Li, Meng Yin, Xiao-Xue Wang, Chen-Yu Wang, Hong-Long Zheng, Shou-Shan Yu, and Ke-Zheng Chen, and Sheng-Lin Qiao*, Layered Double Hydroxide Nanozyme (LDHzyme)-Assisted High-Performance Electrochemical Analysis of Organ Transplant Rejection Drug Concentration. Microchemical Journal 2024, Minor revision.

10. Da-Wei Zhou^1,†, Meng Yin^1,†, Yun Shen^2,†, Xiao-Xue Wang¹, Chen-Yu Wang¹, Ze Wang⁴, Ke-Zheng Chen¹, Qi Fang^3,* and Sheng-Lin Qiao^1,*, LDHzyme-assisted high-performance on-site tracking of levodopa pharmacokinetics for Parkinson’s disease management. Biosensors and Bioelectronics, 2024, Minor revision.

9. Ke Ma^†, Meng Yin^†, Ke-Zheng Chen, and Sheng-Lin Qiao*, Targeted Nanoprobes Enabled Precision Theranostics in Triple-Negative Breast Cancer. under review.

8. Xiao-Chun Yang, Xiao-Xue Wang, Chen-Yu Wang, Meng Yin, Ke Ma, Yan Li, Ke-Zheng Chen, and Sheng-Lin Qiao*, Janus-Adhesive Ionogels for Wearable Real-Time Monitoring and Prevention of Infantile Meningitis. Chemical Engineering Journal 2024, 32, 156197.

7. Xiao-Xue Wang, Chen-Yu Wang, Meng Yin, Ke-Zheng Chen, and Sheng-Lin Qiao*, Tannic Acid-Enabled Antioxidant and Stretchable MXene/Silk Strain Sensors for Diving Training Healthcare. ACS Sensors, 2024, https://doi.org/10.1021/acssensors.4c01091.

6. Xiao-Chun Yang, Xiao-Xue Wang, Chen-Yu Wang, Hong-Long Zheng, Meng Yin, Ke-Zheng Chen, and Sheng-Lin Qiao*, Silk-based intelligent fibers and textiles: Structures, properties, and applications. Chemical Communications, 2024, 60, 7801-7823.

5. Ke Ma, Meng Yin, Xiao-Xue Wang, Chen-Yu Wang, Ke-Zheng Chen, and Sheng-Lin Qiao*, Gold Nanocluster-Based Nanozyme for High-Throughput Colorimetric Detection of SARS-CoV-2. ACS Applied Nano Materials 2024, 7, 10660-10669.

4. Ying-Ao Zhang, Ke Ma, Ke-Zheng Chen, and Sheng-Lin Qiao*, Flexible wearable ionogels: classification, fabrication, properties and applications. Sensors and Actuators: A. Physical 2024, 372, 115325.

3. Ke Wang, Xiao-Xue Wang, Chen-Yu Wang, Meng Yin, Shou-Shan Yu, Ke-Zheng Chen, and Sheng-Lin Qiao*, Customizable and Scalable Manufacture of Aesthetic Ionic Conductive Silk Yarns for E-Textile Devices. Chemical Engineering Journal 2024, 487, 150645.

2. Ke Ma, Ke-Zheng Chen, and Sheng-Lin Qiao*, Advances of Layered Double Hydroxide-Based Materials for Tumor Imaging and Therapy.  Chem. Rec. 2024, e202400010. Cover picture

1. Ying-Ao Zhang, Chen-Yu Wang, Xiao-Xue Wang, Meng Yin, Ke Wang, Da-Wei Zhou, Hong-Long Zheng, Shou-Shan Yu, Shuang Li, Ke-Zheng Chen, and Sheng-Lin Qiao*, Mechanical robust, adhesive, self-healable and biodegradable protein-based electronic skin sensors for smart elderly care. Chemical Engineering Journal 2024, 482, 148785.

2023

3. Yi Wang^†, Sheng-Lin Qiao^†, Jie Wang, Nan-Nan Wang, Muhetaerjiang Mamuti, HongWei An, Yao-Xin Lin*, and Hao Wang*, Engineered CpG-loaded Nanorobots Drive Autophagy-mediated Immunity for TLR9-positive Cancer Therapy. Advanced Materials 2023, 2306248. https://doi.org/10.1002/adma.202306248.

2. Sheng-Lin Qiao*, Ying-Ao Zhang, Ke Wang, Da-Wei Zhou, Zhen-Yi Li, Xiao-Chun Yang,  Shou-Shan Yu, and Ke-Zheng Chen*, Stretchable, Adhesive and Self-Healable Liquid-Free Electron-Conductive Electronics for Wearable Strain Sensors. Advanced Materials Technologies 2023, 8, 2300553.

1. D.-W. Zhou, K. Wang, Y.-A. Zhang, K. Ma, X.-C. Yang, Z.-Y. Li, S.-S. Yu, K.-Z. Chen, and S.-L. Qiao*, mRNA therapeutics for disease therapy: principles, delivery, and clinical translation. J. Mater. Chem. B 2023, 11, 3484-3510. (IF=7.571)

2022

6. S.-J. Liu^†, K. Ma^†, L.-S. Liu^†, K. Wang, Y.-A. Zhang, Z.-R. Bia, Y.-X. Chen, K.-Z. Chen*, C.-X. Wang*, and S.-L. Qiao*. Point-of-care non-invasive enzyme-cleavable nanosensors for acute transplant rejection detection. Biosens. Bioelectron., 2022, 215, 114568.

5. S.-L. Qiao, M. Mamuti, H.-W. An, and H. Wang*. Thermoresponsive Polymer Assemblies: From Molecular Design to Theranostics Application. Prog. Polym. Sci., 2022, 131, 101578.

4. X.-W. Ni, K.-Z. Chen, and S.-L. Qiao*. Photocontrollable Thermosensitive Chemical Spatiotemporally Destabilizeds Mitochondrial Membranes for Cell Fate Manipulation. Biomaterials Science, 2022, 10, 2550-2556. 

3. F.-W. Huang, K. Ma, X.-W. Ni, S.-L. Qiao*, and K.-Z. Chen*. CuCoFe Layered Double Hydroxides as Laccase Mimicking Nanoenzymes for Colorimetric Detection of Pheochromocytoma Biomarkers. Chem. Commun., 2022, 58, 1982-1985. 

2. 倪秀雯，乔圣林*，陈克正*。MXene/F127直写式导电墨水及其在电子皮肤传感器中的应用，青岛科技大学学报，已接收。

1. J. Wang, Y. Wang, S.-L. Qiao, M. Mamuti, H.-W. An, and H. Wang*. In Situ Phase Translational Polymeric Vaccines for Improved Immunotherapy. Natl. Sci. Rev., 2022, 9, nwab159.

Before 2020

25. H.-W. An, L.-L. Li, Y. Wang, Z. Wang, D, Hou, Y.-X. Lin, S.-L. Qiao, M.-D. Wang, C. Yang, Y. Cong, Y. Ma, X.-X. Zhao, Q. Cai, W.-T. Chen, C.-Q. Lu, W. Xu*, H. Wang*, and Y. Zhao*. A Tumour-Selective Cascade Activatable Self-Detained System for Drug Delivery and Cancer Imaging. Nat Commun., 2019, 10, 4861. 

24. Y. Wang^†, Y.-X. Lin^†, J. Wang, S.-L. Qiao, Y.-Y. Liu, W.-Q. Dong, J. Wang, H.-W. An, C. Yang, M. Mamuti, L. Wang, B. Huang, and H. Wang*. In Situ Manipulation of Dendritic Cells by an Autophagy-Regulative Nanoactivator Enables Effective Cancer Immunotherapy, ACS Nano, 2019, 13, 7, 7568.

23. Y. Wang, Y.‐X. Lin, S.-L. Qiao, J. Wang, and H. Wang*. Progress in Tumor‐Associated Macrophages: From Bench to Bedside. Adv. Biosys., 2019, 3, 1800232.

22. S.-L. Qiao, and H. Wang*, Temperature-Responsive Polymers: Synthesis, Properties and Bioapplications. Nano Res., 2018, 11, 5400. 

21. Y. Wang^†, S.-L. Qiao^†, and Hao Wang*, Facile Synthesis of Peptide-Crosslinked Nanogels for Tumor Metastasis Inhibition. ACS Appl. Nano Mater., 2018, 1, 785–792.

20. Y. Ma^†, S.-L. Qiao^†, Y. Wang^†, Y.-X. Lin, H.-W. An, X.-C. Wu, L. Wang, and H. Wang*, Nanoantagonists with Nanophase-Segregated Surfaces for Improved Cancer Immunotherapy. Biomaterials, 2018, 156: 248-257.

19. L.-L. Li^†, S.-L. Qiao^†, W.-J. Liu, Y. Ma, D. Wan, J. Pan, H. Wang*. Intracellular Construction of Topology-Controlled Polypeptide Nanostructures with Diverse Biological Functions. Nat. Commun., 2017, 8, 1276.

18. S.-L. Qiao^†, Y. Ma^†, Y. Wang, Y.-X. Lin, H.-W. An, L.-L. Li*, and H. Wang*. General Approach of Stimuli-Induced Aggregation for Monitoring Tumor Therapy. ACS Nano, 2017, 11, 7301. 

17. Y.-X. Lin, S.-L. Qiao, Y. Wang, R.-X. Zhang, H.-W. An, Y. Ma, R.P.Y.J. Rajapaksha, Z-Y. Qiao, L. Wang*, and H. Wang*. An in situ Intracellular Self-Assembly Strategy for Quantitatively and Temporally Monitoring Autophagy. ACS Nano, 2017, 11, 1826.

16. Y.-X. Lin^†, Y. Wang^†, S.-L. Qiao, H.-W. An, J. Wang, Y. Ma, L. Wang and H. Wang*. “In Vivo Self-Assembled” Nanoprobes for Optimizing Autophagy-Mediated Chemotherapy. Biomaterials, 2017, 141, 199.

15. H.-C. Chen^†, Y.-R. Wang^†, Y.-R. Yao, S.-L. Qiao, H. Wang, N.-H. Tan. Sequential Delivery of Cyclopeptide RA-V and Doxorubicin for Combination Therapy on Resistant Tumor and In Situ Monitoring of Cytochrome c Release. Theranostics, 2017, 7, 3781. 

14. Y.-X. Lin^†, X.-F. Hu^†, Y. Zhao^†, Y.-J. Gao, C. Yang, S.-L. Qiao, Y. Wang, P.-P. Yang, J. Yan, X.-C. Sui, Z.-Y. Qiao, L.-L. Li, J.-B. Xie, S.-Q. Zhu, X.-C. Wu, Y. Li, L. Wang*, and H. Wang*. Photothermal Ring Integrated Intraocular Lens for High-Efficient Eye Disease Treatment. Adv. Mater., 2017, 29, 1701617.  

13. S.-L. Qiao, Y. Wang, Y.-X. Lin, H.-W. An, Y. Ma, L.-L. Li, L. Wang*, H. Wang*. Thermo-Controlled in Situ Phase Transition of Polymer-Peptides on Cell Surfaces for High-Performance Proliferative Inhibition. ACS Appl. Mater. Interfaces, 2016, 8, 17016. 

12. H.-W. An, S.-L. Qiao, L.-L. Li, C. Yang, Y.-X. Lin, Y. Wang, Z.-Y. Qiao, L. Wang*, and H. Wang*. Bio-orthogonally Deciphered Binary Nanoemitters for Tumor Diagnostics. ACS Appl. Mater. Interfaces, 2016, 8, 19202.

11. Z.-Y. Qiao^†, Y.-X. Lin^†, W.-J. Lai, C.-Y. Hou, Y. Wang, S.-L. Qiao, D. Zhang, Q.-J. Fang, and H. Wang*. A General Strategy for Facile Synthesis and in situ Screening of Self-Assembled Polymer-Peptide Nanomaterials. Adv. Mater., 2016, 28, 1859.  

10. Y.-X. Lin, Y. Wang, S.-L. Qiao, H.-W. An, R.-X. Zhang, Z.-Y. Qiao, R.P.Y.J Rajapaksha, L. Wang, and H. Wang*. pH-Sensitive Polymeric Nanoparticles Modulate Autophagic Effect via Lysosome Impairment. Small, 2016, 12, 2921.

9. Y. Wang, Y.-X. Lin, S.-L. Qiao, H.-W. An, Y. Ma, Z.-Y. Qiao, R.P.Y.J. Rajapaksha, H. Wang*. Polymeric Nanoparticles Promote Macrophage Reversal from M2 to M1 Phenotypes in the Tumor Microenvironment. Biomaterials, 2016, 112, 153.

8. L.-M. Hu*, J.-Z. Wu, Z.-P. Li, M. Bu, S.-L. Qiao and H. Wang*. RTG-loaded Nanomicelles(CS-VES-NAC) for Oral Anti-HIV Drug Delivery. RSC Advances, 2016, 6, 75890.

7. H.-W. An, S.-L. Qiao, C.-Y. Hou, Y.-X. Lin, L.-L. Li, H.-Y. Xie, Y. Wang, L. Wang*, H. Wang*. Self-assembled NIR Nanovesicles for Long-term Photoacoustic Imaging in vivo. Chem. Commun., 2015, 51, 13488.

6. S.-J. Liu, S.-L. Qiao, L.-L. Li, G.-B. Qi, Y.-X. Lin, Z.-Y. Qiao, H. Wang* and C. Shao*. Surface Charge-Conversion Polymeric Nanoparticles for Photodynamic Treatment of Urinary Tract Bacterial Infections. Nanotechnology, 2015, 26, 495602-1-12.

5. D. Zhang, G.-B. Qi, Y.-X. Zhao, S.-L. Qiao, C. Yang, and H. Wang*. In Situ Formation of Nanofibers from Purpurin18-Peptide Conjugates and The Assembly-Induced Retention Effect in Tumor Sites. Adv. Mater., 2015, 27, 6125.

4. Z. Duan*, Y.-J. Gao, Z.-Y. Qiao, S.-L. Qiao, Y. Wang, C. Hou, L. Wang* and H. Wang*. pH-Sensitive Polymer Assisted Self-Aggregation of Bis(pyrene) in Living Cells in situ with Turn-on Fluorescence. Nanotechnology, 2015, 26, 355703-1-11. 

3. Y. Wang^†, Y.-X. Lin^†, Z.-Y. Qiao, H.-W. An, S.-L. Qiao, L. Wang, R.P.Y.J. Rajapaksha and H. Wang*. Self-Assembled Autophagy-Inducing Polymeric Nanoparticles for Breast Cancer Interference in-vivo. Adv. Mater., 2015, 27, 2627. 

2. Y.-X. Lin, Y.-J. Gao, Y. Wang, Z.-Y. Qiao, G. Fan, S.-L. Qiao, R.-X. Zhang, L. Wang, H. Wang*. pH-Sensitive Polymeric Nanoparticles with Gold(I) Compound Payloads Synergistically Induce Cancer Cell Death through Modulation of Autophagy. Mol. Pharmatheutics, 2015, 12, 2869.

1. Z.-Y. Qiao, S.-L. Qiao, Y.-S. Fan, Y. Chen, G. Fan and H. Wang*. One-Pot Synthesis of pH-Sensitive Poly(RGD-co-β-Amino Ester) s for Targeted Intracellular Drug Delivery. Poly. Chem., 2014, 5, 844.

授权专利:

6. 王浩; 乔圣林; 马洋; 李莉莉, 一种细胞内构筑温度响应性聚集体的材料及其制备方法和应用, 中国, ZL201710361961.9

5. 王浩;乔圣林;马洋, 一种大分子温敏驱动器及其制备方法和应用, 2019.02.22, 中国, ZL201710361920.X。

4. 王浩; 李莉莉; 安红维; 乔圣林, 中国, 一种药物递送体系及其制备方法与应用, ZL201710891549.8 （已转化）

3. 王浩;王羿; 乔圣林, 一种CpG药物及其制备方法和应用, 中国, ZL201810419839.7

2. 王浩;马洋; 乔圣林; 王羿, 一种表面具有超微结构的纳米拮抗剂的制备方法和应用 中国, ZL201710628855.2

1. 王浩;李莉莉;乔圣林;刘伟娇;马洋, 基于细胞内酶催化聚合的多肽单体分子及其在构建纳米材料中的应用, 2019.06.25, 中国, ZL201610408076.7。

申请专利:

1. 刘仕杰; 乔圣林; 纳宁, 一种用于器官移植排斥检测的即时诊断纳米探针及其应用, 中国, 2022107195560

(10) 2025.01-2026.12 山东省自然科学基金面上基金项目，超小铁氧体纳米酶的多肽模板法绿色制备及其器官移植排斥检测研究，主持

(9) 2023.01-2025.12 国家自然科学基金青年基金项目，胞外ATP响应的纳米传感器在器官移植术后排斥无损检测方面的应用研究，52203174，主持

(8) 2020.01-2025.12 青岛科技大学科研启动经费，1203043003694，主持

(7) 2016.01-2019.12，温敏多肽聚合物在细胞表面的原位组装及其对细胞命运调控的研究，51573032，国家自然基金委面上项目，76万元，参与

(6) 2015.09-2018.09，活体自组装纳米技术用于细菌感染的成像与检测，GJHZ1541，中国科学院国际合作局对外合作重点项目，100万元，参与

(5) 2014.06-2017.06，防治后发性白内障的纳米修饰人工晶状体的研究，Z141100000214008，北京市生命科学领域前沿技术培育专项，410万元，参与

(4) 2013.01-2017.12，纳米材料的代谢过程及其分析方法研究，2013CB932701，科技部973项目，602万元，参与

(3) 2017.01-2020.12，活体超分子纳米组装调控及其在细菌感染诊疗中的应用研究，31671028，65万元，参与

(2) 2015.01-2015.12，基于双芘衍生物的超分子纳米聚集体的制备及其双光子荧光特性研究，51473188，国家自然基金委应急管理项目，15万元，参与

(1) 2016.01-2019.12，超分子荧光纳米材料的性能调控及其双光子生物成像研究，51573031，国家自然基金委面上项目，78万元，参与

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