王鲲鹏   Associate professor

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A highly sensitive and selective turn-on fluorescent sensor for dihydrogen phosphate in living cells

Release time:2023-10-19  Hits:

  • Key Words:Rhodamine 6G; Naphthylurea conjugate; Dihydrophosphate; Fluorescent sensors; Live cell imaging
  • Abstract:A novel visible light excitable chemosensor based on a rhodamine 6G naphthylurea conjugate was successfully synthesized, which shows highly selective and sensitive recognition ability toward H2PO4- in H2O-CH3CN (1/1, v/v). In response to H2PO4-, the probe provided remarkable fluorescence intensity change and clear color change from colorless to pink and the background anions showed small or no interference. The confocal fluorescent images demonstrated that the probe was cell-permeable and could effectively detect intracellular dihydrophosphate in living cells. (C) 2017 Elsevier B.V. All rights reserved.
  • Volume:247
  • Issue:
  • Translation or Not:no