关键字：Scaffolds (biology);Bone - Collagen - Hydroxyapatite - Porosity - Reinforcement - Scaffolds
摘要：Ultralong hydroxyapatite (HAp) micro/nanoribbons were successfully synthesized by a simple hydrothermal method without using any organic solvents and templates. The ultralong HAp micro/nanoribbons were up to several hundred micrometers in length and 100–400 nm in width. The growth process and mechanism of this micro/nanoribbons were also analyzed in this study. Moreover, the ultralong HAp micro/nanoribbons were used as reinforcement in collagen scaffolds and the HAp/collagen composite scaffolds were fabricated by freeze-drying process without cross-linking. The morphological results demonstrated homogeneous interconnected porous structure in 20 wt% and 35 wt% HAp reinforced scaffolds. The compressive modulus of the 35 wt% HAp/collagen composite was about 6 times that of the pure collagen scaffold. The ultralong HAp reinforced collagen scaffold possesses a porous structure, good flexibility as well as elasticity, and thus it is promising for used as bone repair material.<br/> © 2018 Elsevier Ltd and Techna Group S.r.l.
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