- A nitroreductase-activatable near-infrared theranostic photosensitizer for photodynamic therapy under mild hypoxia
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- 关键字：FLUORESCENCE; NANOPARTICLES; PROBE; MITOCHONDRIA
- 摘要：In this study, a near-infrared (NIR) theranostic photosensitizer was developed based on a heptamethine aminocyanine dye with a long-lived triplet state. This theranostic molecule can be activated by nitroreductase under mild hypoxia to be used in fluorescence imaging and highly efficient photodynamic therapy (PDT) both in 2D and 3D (spheroids) HeLa cell culture models.
- 卷号：56
- 期号：43
- 是否译文：否
