教师拼音名称:wuzhongtao
电子邮箱:
学历:博士研究生
办公地点:青岛科技大学四方校区一号实验楼303
性别:男
联系方式:Email:zhongtaowu@163.com QQ:371767897
学位:理学博士
毕业院校:荷兰格罗宁根大学
最后更新时间:..
关键字:AGGREGATION-INDUCED EMISSION; PROTEINS; DESIGN; PROBES
摘要:Solvent-free soft biomaterials with fluorescent property are highly attractive because of their wide prospective applications in bioimaging and anticounterfeiting. However, in solvent-free condition, developing soft fluorescent DNA materials is very challenging. In this study, a type of fluorescent solvent-free DNA thermotropic liquid crystal (DNA-TPEA) is developed via the electrostatic complexation of DNA and tetraphenylethene-containing ammonium surfactant TPEA. Under UV light, DNA-TPEA could give bright luminescence with good quantum yield, which has been tested as an anticounterfeiting labeling biomaterial working at high temperatures and in aqueous condition. An investigation on the photoluminescence lifetime of DNA-TPEA indicates that the TPEA molecules are in two different environments, and for which a working mechanism is illustrated. This work provides a new strategy for developing fluorescent biomaterials in solvent-free condition by fusing AIE surfactants and biomolecules together via electrostatic force, which gains synthetic convenience compared to the covalent modification of biomolecules with fluorescent proteins.
卷号:204
期号:
是否译文:否