王鲲鹏

副教授

副教授 硕士生导师

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学历:博士研究生

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Highly emissive dimethylamino naphthalenyl phenylethene derivatives for visualization of latent fingerprints and imaging of lysosomes

发布时间:2023-10-19 点击次数:

关键字:AGGREGATION-INDUCED EMISSION; PROBES
摘要:Organic fluorescent materials have been widely used in ious fields including visualization of latent fingerprints and imaging of lysosomes. High-performance organic fluorescent molecules based on simple molecular structures are still limited and highly demanded for high-definition and high-contrast imaging of latent fingerprints and lysosomes. In this work, two organic fluorescent molecules (DANPAN and DANBEN) were developed based on dimethylamino naphthalenyl phenylethene structure. These two molecules have quite different fluorescent properties, and the position of cyano group significantly affects the optical properties of these dimethylamino naphthalenyl phenylethene derivatives. Compound DANPAN shows strong yellow emi in solid state, while compound DANBEN has strong fluorescent emi in organic solutions. In addition to these differences, both compounds have large Stokes shifts and positive solvatochromic properties. Further studies showed that these compounds could be used to display latent fingerprints on ious substrate surfaces. The obtained fingerprint images have excellent contrast and high resolution. It is also found that these molecules could specifically stain lysosomes in living cell within short incubation time. This work provides a series of new high-performance organic fluorescent materials with diverse applications.
卷号:205
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