孙瑞雪，青岛科技大学教授，硕士研究生导师。2002年本科毕业于山东大学材料科学与工程专业，2007年博士毕业于山东大学材料学专业（硕博连读）。主要从事生物医用纳米材料的可控制备、性能调控及应用，镁合金表面改性与腐蚀防护等相关领域的研究。先后主持国家自然科学基金、山东省自然科学基金、山东省优秀中青年科研奖励基金等多个科研项目，在Chemical Engineering Journal、Journal of Materials Science &Technology, Applied Surface Science等国内外专业期刊发表论文40余篇，获授权专利5项。

一、承担的科研项目

      1、山东省自然科学基金面上项目，ZR2021ME053，MXene/HAp三维组装体的可控构筑及其对肿瘤细胞的光热 疗-化疗协同作用机制，2022-01至2024-12，在研，主持。

 2、国家自然科学基金青年基金项目，51602169.，基于自身结构特性的羟基磷灰石超长一维微/纳米结构的可控合成、生长机理及其柔韧性，2017-01至2019-12，已结题，主持。 

3、山东省自然科学基金面上项目，ZR2014EMM019，医用镁合金表面羟基磷灰石活性涂层的构及其腐蚀降解调控与生物学行为，2014-12至2017-12，已结题，主持。

4、山东省优秀中青年科研奖励基金项目，BS2010CL018，功能性羟基磷灰石纳米复合结构的可控合成及其与细胞作用机理研究，2011-01至2013-12，已结题，主持。

5、山东省高等学校科技计划项目，J09LC13，多功能磁性荧光羟基磷灰石纳米材料的制备及其应用研究，2009-07至2012-07，已结题，主持。

二、发表的代表性论文

    1. Xiaowei Liu; Ruixue Sun*; Zeao Zhou; Yuanzheng Tang. In situ growth of nanohydroxyapatite on multilayered Ti3C2Tx MXene as a drug carrier with superior-performance, Journal of Materials Science & Technology, 2024, 180: 91-101. 

     2. Fuzhen Li, Ruixue Sun*, Kezheng Chen. Construction and properties of a multifunctional stearic acid modified CeO2 coating on anodized AZ31B Mg alloy,Journal of Alloys and Compounds, 2023, 945: 169316.

    3. Xiaodan Jiang, Xiaowei Liu, Jiayi Cai, Shibo Wei, Yanan Wang, Zhuqing Duan, Zeao Zhou, Ruixue Sun*, Xiaofei Qu*, Yuanzheng Tang. Fabrication and properties of multi-functional polydopamine coated Cu/F-codoped hydroxyapatite hollow microspheres as drug carriers,Colloids and Surfaces B: Biointerfaces, 2023,222, 113097.

   4. Shuaikang Yang; Ruixue Sun*; Kezheng Chen. Self-healing performance and corrosion resistance of phytic acid/cerium composite coating on microarc-oxidized magnesium alloy, Chemical Engineering Journal, 2022, 428: 131198.

    5. Shuaikang Yang; Chen Wang; Fuzhen Li; Naihao Liu; Putong Shi; Baojin Wang; Ruixue Sun*. One-step in situ growth of a simple and efficient pore-sealing coating on micro-arc oxidized AZ31B magnesium alloy, Journal of Alloys and Compounds, 2022, 909: 164710.

     6. Xiaodan Jiang, Yi Zhao, Chen Wang, Ruixue Sun*, Yuanzheng Tang. Effects of physico-chemical properties of ions-doped hydroxyapatite on adsorption and release performance of doxorubicin as a model anticancer drug,Materials Chemistry and Physics, 2022, 276, 125440.

    7. Xiaodan Jiang; Dongqing Zhang; Ruixue Sun*; Huachun Wang; Yuyao Yang; Hongda Guo;Yuanzheng Tang. A combined experimental and molecular dynamics simulation study on doxorubicin adsorption on strontium-substituted hydroxyapatite hollow microspheres, Applied Surface Science, 2021, 542: 148667.

    8. Yi Zhao; Yanhui Qiu; ZiXuan Fang; Fangfang Pu; Ruixue Sun*; Kezheng Chen; Yuanzheng Tang. Preparation and characterization of Sr-substituted hydroxyapatite/reduced graphene oxide 3D scaffold as drug carrier for alendronate sodium delivery, Ceramics International, 2022, 48:36601-36608.

    9. Ruilian Ying, Huachun Wang, Ruixue Sun*, Kezheng Chen; Preparation and properties of a highly dispersed nano-hydroxyapatite colloid used as a reinforcing filler for chitosan, Materials Science & Engineering C, 2020,110:110689.

    10. Wentao Yu, Ruixue Sun*, Ziqiang Guo, Zhiyuan Wang, Yong He, Guangyi Lu, Panyu Chen, Kezheng Chen; Novel fluoridated hydroxyapatite/MAO composite coating on AZ31B magnesium alloy for biomedical application, Applied Surface Science, 2019,464:708-715.

    11. Qing Zhao, Dongqing Zhang, Ruixue Sun*, Shengcong Shang, Huachun Wang, Yuyao Yang, Lian Wang, Xiaokun Liu, Tianxiang Sun, Kezheng Chen; Adsorption behavior of drugs on hydroxyapatite with different morphologies: A combined experimental and molecular dynamics simulation study, Ceramics International, 2019, 45: 19522-19527.

    12. Shengcong Shang, Qing Zhao, Dongqing Zhang, Ruixue Sun*, Yuanzheng Tang; Molecular dynamics simulation of the adsorption behavior of two different drugs on hydroxyapatite and Zn-doped hydroxyapatite, Materials Science & Engineering C, 2019,105:110017.

三、参加的学术会议

    1. 刘晓伟; 孙瑞雪 ; Ti3C2Tx MXene表面纳米羟基磷灰石的原位生长及其药物负载与缓释性能研究,

2023中国生物材料大会, 重庆, 2023-10-12至2023-10-15 (会议报告)

    2. 孙瑞雪; 刘晓伟; 赵毅 ; 羟基磷灰石基复合材料的构建及其药物吸附与缓释性能研究, 2023中国生物

材料学会生物陶瓷分会学术年会暨第三届生物陶瓷材料大会, 温州, 2023-5-12至2023-5-14 (会议报告)

    3. 孙瑞雪; 蒋晓丹; 刘晓伟; 周泽翱 ; 聚多巴胺包覆羟基磷灰石中空微球的制备及其药物吸附性能, 第

一届生物材料与医疗器械赣江学术论坛, 江西南昌, 2023-4-7至2023-4-9 (会议报告)