Adenosine triphosphate responsive metal-organic frameworks equipped with a DNA structure lock for construction of a ratiometric SERS biosensor

发布时间：2021-03-15 点击次数：

• 关键字：ULTRASENSITIVE DETECTION; MOF; RECOGNITION; SENSOR; WATER; RESONANCE; APTAMER
• 摘要：A novel ratiometric surface-enhanced Raman scattering (SERS) biosensor was constructed based on stimuli-responsive DNA functionalized metal organic frameworks (MOFs) for detection of adenosine triphosphate (ATP). As a result, the detection range of ATP was 1 nM to 200 nM with a detection limit of 0.4 nM. The ratiometric SERS biosensor strategy offers a lower detection limit and exhibits a more enhanced performance than the typical SERS detection based on single signal response, which may have potential for detection of other biomolecules or metal ions.
• 卷号：56
• 期号：9
• 是否译文：否