Home > Scientific Research > Paper Publications

A dopamine sensor based on a carbon paste electrode modified with DNA-doped poly(3,4-ethylenedioxythiophene)

Hits:

Key Words:Conducting polymer; Poly (3, 4-ethylenedioxythiophene); DNA; Guanine; Dopamine
Abstract:An electrochemical dopamine sensor was developed by electrochemical modification of a carbon paste electrode with a biocomposite made from poly(3,4-ethylenedioxythiophene) (PEDOT) that was doped with double stranded or single stranded DNA. The resulting conducting biocomposite displays excellent electrocatalytic activity towards the oxidation of dopamine (DA) which is attributed to the presence of the DNA dopant. Under optimum conditions and at a working potential of 300 mV, the modified electrode is capable of detecting DA in the 0.25 to 66 mu M concentration range. The detection limit is 74 nM. The sensor is not interfered by uric acid and ascorbic acid.
Volume:182
Issue:3-4
Translation or Not:no

Pre One:Scaling up an electrochemical signal with a catalytic hairpin assembly coupling nanocatalyst label for DNA detection

Next One:Enhanced catalytic and dopamine sensing properties of electrochemically reduced conducting polymer nanocomposite doped with pure graphene oxide