中文
Home > Scientific Research > Paper Publications

Dendritic amphiphiles of carbosilane dendrimers with peripheral PEG for drug encapsulation

Hits:

  • Key Words:Carbosilane dendrimer; Fluorescence; Encapsulation; Probe molecule

  • Abstract:Amphiphilic dendritic macromolecules are suitable for the noncovalent encapsulation of guest molecules and could potentially be applied in drug-delivery systems. In this work, amphiphilic carbosilane dendrimers with peripheral poly(ethylene glycol) (PEG) units were synthesized using a hydrosilylation reaction, and their encapsulation properties were studied by fluorescence spectroscopy, using pyrene as the probe molecule. The results showed that the encapsulating capacity of the dendrimers increased as the number of PEG units increased, and that it also depended to some degree on the dendrimer generation.

  • Volume:20

  • Issue:8

  • Translation or Not:no

  •

  • PostalAddress:

  • ZipCode:

  • Email:

  • Telephone:
Laoshan Campus-99 Songling Road, Qingdao City, Shandong Province
Sifang Campus-No.53 Zhengzhou Road, Qingdao City, Shandong Province
Sino-German International Cooperation Zone (Sino-German Campus)-No. 3698 Tuanjie Road, West Coast New District, Qingdao City, Shandong Province
Gaomi Campus-No. 1 Xingtan West Street, Gaomi City, Shandong Province
Jinan Campus-No. 80 Wenhua East Road, Jinan City, Shandong Province ©2015 Qingdao University of Science and Technology
Administrator email: master@qust.e		 Click:
  MOBILE Version

The Last Update Time:..