陈克正

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教授 博士生导师 硕士生导师

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Non-superparamagnetic iron-oxide architectures with controlled T<inf>2</inf>contrast ability in magnetic resonance imaging

发布时间:2021-03-15 点击次数:

关键字:Iron oxides;Magnetic resonance imaging - Specific surface area - Superparamagnetism;Antiferromagnetics - Contrast agent - Langevin functions - Morphology and structures - Superparamagnetic iron oxides - T2 contrast
摘要:In this work, numerous antiferromagnetic (AFM) and weak ferromagnetic (WFM) iron oxides were fabricated and used as contrast agents in magnetic resonance imaging application. These non-superparamagnetic iron oxides exhibit r<inf>2</inf>/r<inf>1</inf>ratios in a range of 20-110, and hence making them potential for T<inf>2</inf>contrast enhancers. Most strikingly, a Langevin-function relationship was found between r<inf>2</inf>/r<inf>1</inf>ratios and the specific surface area (S) values, r<inf>2</inf>/r<inf>1</inf>∼L<sup>-2</sup>(S<sup>-1</sup>), which is quite unique for AFM and WFM iron oxides. This finding enables us to precisely tailor their r<inf>2</inf>/r<inf>1</inf>ratios simply by manipulating their specific surface area via controlling morphology and structure in preparation.<br/> © 2015 AIP Publishing LLC.
卷号:107
期号:7
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