Abstract:Particle size is normally thought to be a major factor to evaluate MRI performance of contrast agents in biological systems. In this regard, three size-relevant regimes, including motional averaging regime, static dephasing regime, and echo-limited regime, have been well developed. In this study, we find the dispersant, which is often used as the subordinate additive in MRI measurements, is another key factor that determines the application of these three regimes in real systems. Our results show that the identically sized particle systems can separately exhibit static dephasing and echo-limited behaviors merely by altering the dispersants in aqueous solution. (C) 2015 AIP Publishing LLC.

Volume:117

Issue:15

Translation or Not:no